منابع مشابه
Integrity of the cone photoreceptor mosaic in oligocone trichromacy.
PURPOSE Oligocone trichromacy (OT) is an unusual cone dysfunction syndrome characterized by reduced visual acuity, mild photophobia, reduced amplitude of the cone electroretinogram with normal rod responses, normal fundus appearance, and normal or near-normal color vision. It has been proposed that these patients have a reduced number of normal functioning cones (oligocone). This paper has soug...
متن کاملNoninvasive imaging of the photoreceptor mosaic response to light stimulation.
In their latest work, Hillman et al. (1) observe optical path length changes of individual photoreceptor cells in response to light stimulation, noninvasively, in a living human subject. This is a remarkable technical feat, showing the reliable extraction of nanometer-scale changes across the photoreceptor mosaic, although involuntary motion of the target tissue is up to five orders of magnitud...
متن کاملPhotopigment transmittance imaging of the primate photoreceptor mosaic.
We introduce a new technique for classifying many photoreceptors simultaneously in fresh, excised primate retina on the basis of their absorptance spectra. Primate retina is removed from the pigment epithelium and illuminated under a microscope from the same direction as in the intact eye. To facilitate the guiding of light into the receptor outer segments, the optical axes of the photoreceptor...
متن کاملCharacterizing the Human Cone Photoreceptor Mosaic via Dynamic Photopigment Densitometry
Densitometry is a powerful tool for the biophysical assessment of the retina. Until recently, this was restricted to bulk spatial scales in living humans. The application of adaptive optics (AO) to the conventional fundus camera and scanning laser ophthalmoscope (SLO) has begun to translate these studies to cellular scales. Here, we employ an AOSLO to perform dynamic photopigment densitometry i...
متن کاملNoninvasive imaging of the thirteen-lined ground squirrel photoreceptor mosaic.
Ground squirrels are an increasingly important model for studying visual processing, retinal circuitry, and cone photoreceptor function. Here, we demonstrate that the photoreceptor mosaic can be longitudinally imaged noninvasively in the 13-lined ground squirrel (Ictidomys tridecemlineatus) using confocal and nonconfocal split-detection adaptive optics scanning ophthalmoscopy using 790 nm light...
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ژورنال
عنوان ژورنال: Eye
سال: 1998
ISSN: 0950-222X,1476-5454
DOI: 10.1038/eye.1998.142